GPCRmd

Protein Information: Probable G-protein coupled receptor 34

Cannonical Uniprot Accesion Number: Q9UPC5

        10         20         30         40         50
MRSHTITMTT TSVSSWPYSS HRMRFITNHS DQPPQNFSAT PNVTTCPMDE 
        60         70         80         90        100
KLLSTVLTTS YSVIFIVGLV GNIIALYVFL GIHRKRNSIQ IYLLNVAIAD 
       110        120        130        140        150
LLLIFCLPFR IMYHINQNKW TLGVILCKVV GTLFYMNMYI SIILLGFISL 
       160        170        180        190        200
DRYIKINRSI QQRKAITTKQ SIYVCCIVWM LALGGFLTMI ILTLKKGGHN 
       210        220        230        240        250
STMCFHYRDK HNAKGEAIFN FILVVMFWLI FLLIILSYIK IGKNLLRISK 
       260        270        280        290        300
RRSKFPNSGK YATTARNSFI VLIIFTICFV PYHAFRFIYI SSQLNVSSCY 
       310        320        330        340        350
WKEIVHKTNE IMLVLSSFNS CLDPVMYFLM SSNIRKIMCQ LLXHDTSVAV 
       360
KIQSSSKST

Scientific name: Homo sapiens

Is this protein a mutant? True

Mutations:

Residue 365: From L to X

Residue 343: From F to -

Residue 344: From R to -

Residue 345: From R to -

Residue 346: From F to -

Residue 347: From Q to -

Residue 348: From G to -

Residue 349: From E to -

Residue 350: From P to -

Residue 351: From S to -

Residue 352: From R to -

Residue 353: From S to -

Residue 354: From E to -

Residue 355: From S to -

Residue 356: From T to -

Residue 357: From S to -

Residue 358: From E to -

Residue 359: From F to -

Residue 360: From K to -

Residue 361: From P to -

Residue 362: From G to -

Residue 363: From Y to -

Residue 364: From S to -

Corresponding Cannonical Protein:

Protein ID: 1623

You can find this protein in the following complex structures:

Complex Structure ID: 1756 Complex Structure ID: 1335 Complex Structure ID: 1752 Complex Structure ID: 1750 Complex Structure ID: 1753 Complex Structure ID: 1754 Complex Structure ID: 1755 Complex Structure ID: 1758 Complex Structure ID: 1759 Complex Structure ID: 1760 Complex Structure ID: 1761 Complex Structure ID: 1757

References in which this protein is mentioned:

Tamaki Izume, Ryo Kawahara, Akiharu Uwamizu, Luying Chen, Shun Yaginuma, Jumpei Omi, Hiroki Kawana, Fengjue Hou, Fumiya K. Sano, Tatsuki Tanaka, Kazuhiro Kobayashi, Hiroyuki H. Okamoto, Yoshiaki Kise, Tomohiko Ohwada, Junken Aoki, Wataru Shihoya, Osamu Nureki. 2024. Structural basis for lysophosphatidylserine recognition by GPR34. Nature Communications 15 (None). doi: doi.org/10.1038/s41467-024-45046-z. Available in: Pubmed Link