Publications
Sadler, Fredrik and Ma, Ning and Ritt, Michael and Sharma, Yatharth and Vaidehi, Nagarajan and Sivaramakrishnan, Sivaraj. 2023. Autoregulation of GPCR signalling through the third intracellular loop. Nature 615 (7953). doi: 10.1038/s41586-023-05789-z. (http://dx.doi.org/10.1038/s41586-023-05789-z)
Dynamic id | Receptor | Model name | Uniprot entry name | Uniprot ID | Family | Class | PDB ID | State | Species | Model type | Source type | Ligand(s) | Num. of atoms | Membrane composition | Accum. sim. time (µs) | Software | Force field | Submitted by | ||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
View | 1247 | Beta-2 adrenergic receptor | B2AR-ICL3 | adrb2_human | P07550 | Adrenoceptors | A | 6E67 | Active | Homo sapiens | Complex | Electron microscopy (CryoEM) | Chembl579394 | 5169 | 17.80 | GROMACS 2021.3 | CHARMM 36m | Nagarajan Vaidehi, Beckman Research Institute of the City of Hop | Report |